Newsletter

Flat and boring

Hey Reader, Dr Karl here. Flat and boring. If you have ever worn a continuous glucose monitor, you already know what I am about to show you, and you probably did not know it was the point. Four years ago her CGM trace was jagged. Peaks, drops, more peaks. Today it is a low flat line that barely moves all day. Flat and ...

Her fasting insulin was 9.6. Her doctor said she was fine

Hey Reader, Dr Karl here. Nine point six. ​That is where her fasting insulin sat four years ago. On a Labcorp range runs 2.6–24.9 µIU/mL so 9.6 prints without a flag. ...

What The People Who Live Longest Have In Common

Hey Reader, Dr Karl here. It shows up in the data, and it's the opposite of what most people track. When I plot my clients by age, something shows up that I didn't go looking for. The older people in my data — the ones still healthy, still going — have a much lower fasting insulin. Not lower cholesterol. Not lower weight, ...

He got Fired From Harvard For This One Lab Test

Hey Reader, Dr Karl here. It predicts dementia and heart disease. Almost nobody orders it.And he got Fired from his lab at Harvard when no one would support his research. In the late 1990s a researcher named Kilmer McCully was working at Harvard on a marker called homocysteine. He thought it explained a great deal about heart ...

The Panel To Actually Run — And What It Costs You Not To

Hey Reader, Dr Karl here. Six labs. Most doctors won't order half of them. Over the last two weeks I've shown you my own numbers at 70 — the pairings, the surprise, and why "in range" told me almost nothing. So here's the practical end of it. If you want to know where you actually stand, this is the short list: Fasting ...